tag:blogger.com,1999:blog-7315236707728759521.post8541773261493125193..comments2024-03-28T21:52:52.100-06:00Comments on Dispatches From Turtle Island: Sardinian Population GeneticsAndrew Oh-Willekehttp://www.blogger.com/profile/02537151821869153861noreply@blogger.comBlogger3125tag:blogger.com,1999:blog-7315236707728759521.post-45033881802891738512016-12-12T04:13:27.445-07:002016-12-12T04:13:27.445-07:00Older introduction to Sardinia as haplotype is con...Older introduction to Sardinia as haplotype is considerably more equilibrated. Entry probably in the order of 7 or 8 kya+ minimum. Haplotype is much less equilibrated in Basques, so entry might be more like <5kya. On the Wikipedia entry the author states that the Basque and Sardinian haplotypes had a different Cw allele, but looking on allelefrequencies.net one can see that they are definitely the same.Anonymoushttps://www.blogger.com/profile/13013399855770625556noreply@blogger.comtag:blogger.com,1999:blog-7315236707728759521.post-3167109222026697632016-12-11T17:08:20.988-07:002016-12-11T17:08:20.988-07:00I wonder if there is any way to date when those en...I wonder if there is any way to date when those entered the genomes in question. I can think of plausible narratives for later introductions in both Basque and Sardinia in more recent times, although different for each.andrewhttps://www.blogger.com/profile/08172964121659914379noreply@blogger.comtag:blogger.com,1999:blog-7315236707728759521.post-10834524375191587652016-12-11T05:10:38.178-07:002016-12-11T05:10:38.178-07:00"Why Is There A Basque Affinity In Sardinian ..."Why Is There A Basque Affinity In Sardinian Population Genetics?"<br /><br />https://en.wikipedia.org/wiki/A30-Cw5-B18-DR3-DQ2_(HLA_Haplotype)<br /><br />The HLA haplotype A30-Cw5-B18-DR3-DQ2 is instructive. This is the #1 HLA haplotype in Sardinia. It appears to have formed in northern Africa, migrated to Sardinia early on, reached high frequency in Sardinia due to founder effect / drift, and then entered mainland Europe with second highest European frequency in Basques. The full haplotype, or variations on it, can be found in Maghrebi Berbers, Senegalese Mandenka, Ghanaians, Chadic speakers in north Cameroon, Sudanese, and Kenyan Luo [although Africa is badly under-sampled].<br /><br />Italy Sardinia Pop.3 - 12.50% [highest-frequency class I HLA haplotype in Sardinia]<br />Spain Gipuzkoa Basque - 6.10% [second-highest frequency class I HLA haplotype in Basques]<br />Portugal South - 4.10%<br />Spain Murcia - 3.50%<br />Spain Majorca & Minorca - 2.20%<br />France Corsica Island - 2.00%<br />Spain Catalonia Girona - 1.70%<br />Spanish expats/migrants in Germany - 1.57%<br />Portugal Beja - 1.50%<br />Italy Pop. 5 - 1.26%<br />Portugal Faro - 1.20%<br />Portugal North - 1.10%<br />Italian expats/migrants in Germany - 0.95%<br />Portuguese expats/migrants in Germany - 0.81%<br />Romanian expats/migrants in Germany - 0.41%<br />Albanian Pop.2 - 0.12%<br />Greek expats/migrants in Germany - 0.11%<br />Russia Moscow Pop.2 - 0.10%<br />Germany Pop.7 - 0.10%<br />Poland DKMS - 0.09%<br />Anonymoushttps://www.blogger.com/profile/13013399855770625556noreply@blogger.com