We know that the plague was in Britain around 2000 BCE (the earliest known cases in Britain) based upon ancient plague DNA from that time period, according to the press release for the journal article: Pooja Swali, et al., "Yersinia pestis genomes reveal plague in Britain 4000 years ago." 14(1) Nature Communications (2023) DOI: 10.1038/s41467-023-38393-w
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