Saturday, December 31, 2022
Keeping Up With The AI Competition
Thursday, December 29, 2022
Mehmed v. Vlad
Tuesday, December 27, 2022
Genetics Favor Domestication Of Cats In The Near East
Cat domestication likely initiated as a symbiotic relationship between wildcats (Felis silvestris subspecies) and the peoples of developing agrarian societies in the Fertile Crescent. As humans transitioned from hunter-gatherers to farmers ~12,000 years ago, bold wildcats likely capitalized on increased prey density (i.e., rodents). Humans benefited from the cats’ predation on these vermin. To refine the site(s) of cat domestication, over 1000 random-bred cats of primarily Eurasian descent were genotyped for single-nucleotide variants and short tandem repeats. The overall cat population structure suggested a single worldwide population with significant isolation by the distance of peripheral subpopulations. The cat population heterozygosity decreased as genetic distance from the proposed cat progenitor’s (F.s. lybica) natural habitat increased. Domestic cat origins are focused in the eastern Mediterranean Basin, spreading to nearby islands, and southernly via the Levantine coast into the Nile Valley. Cat population diversity supports the migration patterns of humans and other symbiotic species
Friday, December 23, 2022
The Aztec Calendar Worked
Without clocks or modern tools, ancient Mexicans watched the sun to maintain a farming calendar that precisely tracked seasons and even adjusted for leap years.
Thursday, December 22, 2022
Another Global Constraint On BSM Physics
The Standard Model cannot explain the dominance of matter over anti-matter in our universe. This imbalance indicates undiscovered physics that violates combined CP symmetry.
Many extensions to the Standard Model seek to explain the imbalance by predicting the existence of new particles. Vacuum fluctuations of the fields associated with these new particles can interact with known particles and make small modifications to their properties; for example, particles which violate CP symmetry will induce an electric dipole moment of the electron (eEDM). The size of the induced eEDM is dependent on the masses of the new particles and their coupling to the Standard Model. To date, no eEDM has been detected, but increasingly precise measurements probe new physics with higher masses and weaker couplings.
Here we present the most precise measurement yet of the eEDM using electrons confined inside molecular ions, subjected to a huge intra-molecular electric field, and evolving coherently for up to 3 seconds. Our result is consistent with zero and improves on the previous best upper bound by a factor ∼2.4. Our sensitivity to 10^−19 eV shifts in molecular ions provides constraints on broad classes of new physics above 10^13 eV, well beyond the direct reach of the LHC or any other near- or medium-term particle collider.
Native American Solstice Ceremonies
The winter solstice is the day of the year when the Northern Hemisphere has the fewest hours of sunlight and the Southern Hemisphere has the most. For indigenous peoples, it has been a time to honor their ancient sun deity. They passed their knowledge down to successive generations through complex stories and ritual practices.
An Insight Into QCD Math Has The Potential To Rock QCD Phenomenology
We show that the topological charge of nonabelian gauge theory is unphysical by using the fact that it always involves the unphysical gauge field component proportional to the gradient of the gauge function. The removal of Gribov copies, which may break the Becchi-Rouet-Stora-Tyutin symmetry, is irrelevant thanks to the perturbative one-loop finiteness of the chiral anomaly. The unobservability of the topological charge immediately leads to the resolution of the Strong CP problem. We also present important consequences such as the physical relevance of axial U(1) symmetry, the θ-independence of vacuum energy, the unphysicalness of topological instantons, and the impossibilities of realizing the sphaleron induced baryogenesis as well as the chiral magnetic effect. The unphysical vacuum angle and the axial U(1) symmetry also imply that the CP phase of the Cabibbo-Kobayashi-Maskawa matrix is the sole source of CP violation of the standard model.
Wednesday, December 21, 2022
The Triumphant Standard Model
Tuesday, December 20, 2022
The Sumerian Roots Of the Menorah
The Old European Culture blog in yet another thought provoking post muses on possible Sumerian roots of the Menorah in Jewish culture.
Lepton Universality Violations Have Disappeared With Improved LHC Data
The first simultaneous test of muon-electron universality using B+→K+ℓ+ℓ− and B0→K∗0ℓ+ℓ− decays is performed, in two ranges of the dilepton invariant-mass squared, q2. The analysis uses beauty mesons produced in proton-proton collisions collected with the LHCb detector between 2011 and 2018, corresponding to an integrated luminosity of 9 fb−1. Each of the four lepton universality measurements reported is either the first in the given q2 interval or supersedes previous LHCb measurements. The results are compatible with the predictions of the Standard Model.
A simultaneous analysis of the B+→K+ℓ+ℓ− and B0→K∗0ℓ+ℓ− decays is performed to test muon-electron universality in two ranges of the square of the dilepton invariant mass, q2. The measurement uses a sample of beauty meson decays produced in proton-proton collisions collected with the LHCb detector between 2011 and 2018, corresponding to an integrated luminosity of 9 fb−1. A sequence of multivariate selections and strict particle identification requirements produce a higher signal purity and a better statistical sensitivity per unit luminosity than previous LHCb lepton universality tests using the same decay modes. Residual backgrounds due to misidentified hadronic decays are studied using data and included in the fit model. Each of the four lepton universality measurements reported is either the first in the given q2 interval or supersedes previous LHCb measurements. The results are compatible with the predictions of the Standard Model.
Saturday, December 17, 2022
LHC To Announce Its Lepton Universality Violation Results On Tuesday
Experimental results tending to show lepton universality violations (i.e. a different probability for decays to tau leptons, muons, and electron-positron pairs respectively, mass-energy conservation permitting) are the most notable experimental anomalies from Standard Model predictions outstanding right now in high energy physics.
But the statistical significance is merely a tension that may fade with a major new data point like the one to be announced on Tuesday, and there isn't a good explanation for why it isn't seen in other phenomena that should involve the same intermediate W boson decay driven processes.
Measurements of 𝑅(𝐾) and 𝑅(𝐾∗) with the full LHCb Run 1 and 2 databy Renato Quagliani (EPFL - Ecole Polytechnique Federale Lausanne (CH))In this seminar we present the first simultaneous test of muon-electron universality in 𝐵+→𝐾+ℓ+ℓ− and 𝐵0→𝐾∗0ℓ+ℓ− decays, known as 𝑅(𝐾) and 𝑅(𝐾∗), in two regions of di-lepton invariant mass squared.The analysis operates at a higher signal purity compared with previous analyses and implements a data-driven treatment of residual hadronic backgrounds. The analysis uses the full LHCb Run 1 and 2 data recorded in 2011-2012 and 2015-2018, corresponding to an integrated luminosity of 9 fb−1. This analysis is the most sensitive lepton universality test in rare b-decays and the results obtained supersede the previous LHCb measurements of 𝑅(𝐾) and 𝑅(𝐾∗0).
Tuesday, December 13, 2022
Old Water
Water is crucial for the emergence and evolution of life on Earth. Recent studies of the water content in early forming planetary systems similar to our own show that water is an abundant and ubiquitous molecule, initially synthesized on the surfaces of tiny interstellar dust grains by the hydrogenation of frozen oxygen. Water then enters a cycle of sublimation/freezing throughout the successive phases of planetary system formation, namely, hot corinos and protoplanetary disks, eventually to be incorporated into planets, asteroids, and comets. The amount of heavy water measured on Earth and in early forming planetary systems suggests that a substantial fraction of terrestrial water was inherited from the very first phases of the Solar System formation and is 4.5 billion years old.
Friday, December 9, 2022
New mtDNA Clade Discovered
I missed this paper when it came out, but found it now that it has won an editor's choice award, as one of its authors explained at their blog.
As background, the Sandawe people in whom the new clade is found, are East African desert/savanna hunter-gatherers who speak a click language, while the Mbuti people, in whom the sister mtDNA clade L5 is found, are African pygmies found in the Congo jungle (their ancestral language was lost, mostly to Bantu languages, before it was ever attested).
Archaeological and genomic evidence suggest that modern Homo sapiens have roamed the planet for some 300–500 thousand years. In contrast, global human mitochondrial (mtDNA) diversity coalesces to one African female ancestor (“Mitochondrial Eve”) some 145 thousand years ago, owing to the ¼ gene pool size of our matrilineally inherited haploid genome. Therefore, most of human prehistory was spent in Africa where early ancestors of Southern African Khoisan and Central African rainforest hunter-gatherers (RFHGs) segregated into smaller groups. Their subdivisions followed climatic oscillations, new modes of subsistence, local adaptations, and cultural-linguistic differences, all prior to their exodus out of Africa. Seven African mtDNA haplogroups (L0–L6) traditionally captured this ancient structure—these L haplogroups have formed the backbone of the mtDNA tree for nearly two decades.
Here we describe L7, an eighth haplogroup that we estimate to be ~ 100 thousand years old and which has been previously misclassified in the literature. In addition, L7 has a phylogenetic sublineage L7a*, the oldest singleton branch in the human mtDNA tree (~ 80 thousand years). We found that L7 and its sister group L5 are both low-frequency relics centered around East Africa, but in different populations (L7: Sandawe; L5: Mbuti). Although three small subclades of African foragers hint at the population origins of L5'7, the majority of subclades are divided into Afro-Asiatic and eastern Bantu groups, indicative of more recent admixture. A regular re-estimation of the entire mtDNA haplotype tree is needed to ensure correct cladistic placement of new samples in the future.
Thursday, December 8, 2022
The Latest CKM Matrix Fit
The CKM matrix, which can be reduced to four parameters, quantifies the likelihood of quarks transforming into different kinds of quarks in W boson mediated weak force interactions. The latest global fit of those Standard Model parameters are as follows:
A New Branch Of The Tree Of Life
The tree of life is a useful diagram for understanding the relationships between different forms of life, present and extinct. The trunks are made up of three broad groups called domains – Bacteria, Archaea and Eukaryota – which then branch into kingdoms such as animals and fungi. From there the branches become more and more specific until you reach individual species.The new discovery adds quite a major bough to the tree – Provora. These lifeforms make up a category informally called a “supergroup,” which sits below domains and can contain multiple kingdoms.“This is an ancient branch of the tree of life that is roughly as diverse as the animal and fungi kingdoms combined, and no one knew it was there,” said Dr. Patrick Keeling, senior author of the study.Members of the Provora supergroup are tiny organisms that the team describes as the “lions of the microbial world.” That’s because they prey upon other microbes, and within their ecosystem they’re relatively rare. The supergroup is further divided into two clades – the “nibblerids,” which use tooth-like structures to nibble chunks off their prey, and the “nebulids,” which engulf their prey whole.The team discovered this new kind of life in samples taken from around the world, including the coral reefs in Curaçao, sediment from the Black and Red seas and water from the Pacific and Arctic oceans. . . .“In the taxonomy of living organisms, we often use the gene ‘18S rRNA’ to describe genetic difference,” said Dr. Denis Tikhonenkov, first author of the study. “For example, humans differ from guinea pigs in this gene by only six nucleotides. We were surprised to find that these predatory microbes differ by 170 to 180 nucleotides in the 18S rRNA gene from every other living thing on Earth. It became clear that we had discovered something completely new and amazing.”
Molecular phylogenetics of microbial eukaryotes has reshaped the tree of life by establishing broad taxonomic divisions, termed supergroups, that supersede the traditional kingdoms of animals, fungi and plants, and encompass a much greater breadth of eukaryotic diversity. The vast majority of newly discovered species fall into a small number of known supergroups.
Recently, however, a handful of species with no clear relationship to other supergroups have been described, raising questions about the nature and degree of undiscovered diversity, and exposing the limitations of strictly molecular-based exploration.
Here we report ten previously undescribed strains of microbial predators isolated through culture that collectively form a diverse new supergroup of eukaryotes, termed Provora. The Provora supergroup is genetically, morphologically and behaviourally distinct from other eukaryotes, and comprises two divergent clades of predators—Nebulidia and Nibbleridia—that are superficially similar to each other, but differ fundamentally in ultrastructure, behaviour and gene content.
These predators are globally distributed in marine and freshwater environments, but are numerically rare and have consequently been overlooked by molecular-diversity surveys. In the age of high-throughput analyses, investigation of eukaryotic diversity through culture remains indispensable for the discovery of rare but ecologically and evolutionarily important eukaryotes.
Tuesday, December 6, 2022
Did Archaic Hominins Use Fire?
Ancient DNA From 2000 BCE Hair Of A Herder In Sudan
A new study has analyzed ancient DNA and other chemical features of hair from an individual who died around 2000 BCE and was interred in Sudan. The open access source paper is here. As Bernard explains at this blog (at the link):
This individual is dated 4033 years in the Kerma period which succeeds the Neolithic.A recent study on the diet of individuals buried in Kadruka cemeteries showed that these individuals ate dairy products from cows or sheep, C3-type plants such as beans, cowpeas, cassava, soybeans, rice or barley, or animals eating type C3 plants. The early proliferation of the pastoral economy visible in the Kerma culture of northern Sudan has been proposed as a potential source for the spread of pastoralism in East Africa. . . .
The results show that the ancient individual from northern Sudan is located close to the ancient pastors of East Africa, particularly Kenya and Tanzania, also dated 4000 years ago. Moreover, the f3 statistic shows that this individual from Sudan has the most genetic affinity with the ancient individuals of the Levant, the ancient individuals of North or East Africa, or the current populations of North Africa or the Horn of Africa.These results suggest that the pastoral economy has spread in Africa along the banks of the Nile, towards the south.
Monday, December 5, 2022
Ancient DNA From Sri Lanka
The samples are only mtDNA and are from roughly 3500 BCE and 7500 BCE respectively, both predating the South Indian Neolithic Revolution. Both are mtDNA haplogroups generally associated with higher proportions of Ancient Ancestral South Indian autosomal DNA in modern populations and less old ancient DNA samples.
As expected, continuity from pre-farming times is greater for mtDNA which passes from mother to child, than for Y-DNA for which modern South Asia shows dramatic change from pre-farming eras, since in South Asia, genetic change was associated with conquest by male dominated groups that took local wives more often than colonization by gender balanced families.
Sri Lanka is an island in the Indian Ocean connected by the sea routes of the Western and Eastern worlds. Although settlements of anatomically modern humans date back to 48,000 years, to date there is no genetic information on pre-historic individuals in Sri Lanka.
We report here the first complete mitochondrial sequences for Mesolithic hunter-gatherers from two cave sites. The mitochondrial haplogroups of pre-historic individuals were M18a and M35a. Pre-historic mitochondrial lineage M18a was found at a low prevalence among Sinhalese, Sri Lankan Tamils, and Sri Lankan Indian Tamil in the Sri Lankan population, whereas M35a lineage was observed across all Sri Lankan populations with a comparatively higher frequency among the Sinhalese. Both haplogroups are Indian derived and observed in the South Asian region and rarely outside the region.
A. S. Fernando, et al., "The mitochondrial genomes of two Pre-historic Hunter Gatherers in Sri Lanka" J Hum Genet (November 30, 2022). https://doi.org/10.1038/s10038-022-01099-w







